Researchers edit beagle embryos to remove a major dog allergen

Researchers tested saliva and dander from the gene-edited dogs and found no detectable Can f 1 protein. The resulting 25 reconstructed embryos were implanted into a surrogate beagle, which eventually gave birth to Alfie and Bailey.Dogs are often called humans’ best friend, but for people with dog allergies, living with a canine companion can be difficult or even impossible. Now, researchers have taken a step toward creating dogs that may be easier for some allergy sufferers to live with. According to online reports, scientists at Kindred Companion Sciences have used CRISPR, the Nobel Prize-winning gene-editing technology, to remove a gene responsible for producing Can f 1, one of the major proteins associated with dog allergies. The work, published August 5 in the CRISPR Journal, resulted