JNCASR scientists develop smartphone-based diagnostic system for detection of Alzheimer’s disease

Alzheimer’s is a progressive neurodegenerative disorder characterised by memory loss, cognitive decline, and behavioural impairment. Scientists at the Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) have developed a low-cost, user-friendly point-of-care diagnostic system for the detection of Alzheimer’s.The system uses a smartphone-enabled platform employing a fluorescence-responsive tiny molecule to help in the detection of the Alzheimer’s biomarker amyloid-β (Aβ).Alzheimer’s is a progressive neurodegenerative disorder characterised by memory loss, cognitive decline, and behavioural impairment.Central to its pathology is the misfolding and aggregation of amyloid-β (Aβ), which self-assembles into fibrils and deposits as extracellular plaques that trigger neurotoxic cascad